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There are 4 words beginning with SUBSTITUTIO

SUBSTITUTION	• substitution n. The act of substituting or the state of being substituted. • substitution n. A substitute or replacement. • substitution n. (Chemistry, especially organic chemistry) The replacement of an atom, or group of atoms, in a compound, with another.
SUBSTITUTIONS	• substitutions n. Plural of substitution. • SUBSTITUTION n. the act of substituting one thing for another.
SUBSTITUTIONAL	• substitutional adj. Of or pertaining to substitution or to a substitute. • SUBSTITUTIONAL adj. relating to substitution.
SUBSTITUTIONARY	• substitutionary adj. Of or relating to substitution or replacement. • SUBSTITUTIONARY adj. relating to substitution.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 11 words
Scrabble in French: 2 words
Scrabble in Spanish: no word
Scrabble in Italian: no word
Scrabble in German: no word
Scrabble in Romanian: no word

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