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There are 2 six-letter words beginning with SPRAI

SPRAID	• spraid adj. (UK, dialect, obsolete) Alternative form of sprayed (“chapped with cold”). • SPRAY v. to disperse in fine particles.
SPRAIN	• sprain v. To weaken, as a joint, ligament, or muscle, by sudden and excessive exertion, as by wrenching; to overstrain… • sprain n. The act or result of spraining; lameness caused by spraining. • SPRAIN v. to injure by twisting or wrenching.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 2 words
Scrabble in French: 1 word
Scrabble in Spanish: no word
Scrabble in Italian: no word
Scrabble in German: no word
Scrabble in Romanian: 1 word

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