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There are 16 words ending with LESOME

DOLESOME	• dolesome adj. Doleful; dismal; gloomy. • DOLESOME adj. doleful, dismal.
HOLESOME	• holesome adj. Obsolete form of wholesome. • HOLESOME adj. (Spenser) wholesome, also HEALSOME, HOLESOM.
TOYLESOME	• toylesome adj. Obsolete form of toilsome. • TOYLESOME adj. (Spenser) toilsome, also TOYLSOM.
WHOLESOME	• wholesome adj. Promoting good physical health and well-being. • wholesome adj. Promoting moral and mental well-being. • wholesome adj. Favourable to morals, religion or prosperity; sensible; conducive to good; salutary; promoting virtue…
BUNGLESOME	• bunglesome adj. Characterised or marked by bungling; ungainly; awkward; incompetent. • BUNGLESOME adj. clumsy, awkward.
CUDDLESOME	• cuddlesome adj. Characterised or marked by cuddling; cuddly. • CUDDLESOME adj. cuddly.
GIGGLESOME	• gigglesome adj. Characterised or marked by giggling. • GIGGLESOME adj. inclined to giggle, giggly.
MEDDLESOME	• meddlesome adj. Characterised or marked by meddling; inclined or having a tendency to meddle or interfere in other people’s… • MEDDLESOME adj. given to meddling.
METTLESOME	• mettlesome adj. Marked by mettle or bravery; courageous. • METTLESOME adj. full of mettle.
NETTLESOME	• nettlesome adj. (Of a person, thing, situation, etc.) Causing irritation, annoyance, or discomfort; bothersome, irksome. • nettlesome adj. (Of a task, problem, etc.) Thorny; difficult to deal with, especially due to being complex or tricky. • NETTLESOME adj. causing vexation.
TANGLESOME	• tanglesome adj. Characterised or marked by entanglement, tangled, entangled. • tanglesome adj. (UK, dialect) Quarrelsome. • TANGLESOME adj. causing entanglement.
CHUCKLESOME	• chucklesome adj. Causing chuckles; humorous. • CHUCKLESOME adj. full of chuckles.
TROUBLESOME	• troublesome adj. Causing trouble or anxiety. • TROUBLESOME adj. causing trouble.
UNWHOLESOME	• unwholesome adj. Not wholesome; unfavorable to health; unhealthful. • unwholesome adj. Not sound; tainted; defective. • unwholesome adj. Indicating unsound health; characteristic of or suggesting an unsound condition, physical or mental;…
WHEEDLESOME	• wheedlesome adj. Characterised or marked by wheedling; coaxing, cajoling. • WHEEDLESOME adj. coaxing.
WRANGLESOME	• wranglesome adj. Characterised or marked by wrangling; inclined to wrangle or squabble; quarrelsome. • WRANGLESOME adj. quarrelsome.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 120 words
Scrabble in French: no word
Scrabble in Spanish: no word
Scrabble in Italian: no word
Scrabble in German: no word
Scrabble in Romanian: no word

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