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There are 6 seven-letter words containing DESP

DESPAIR• despair v. (Transitive, obsolete) To give up as beyond hope or expectation; to despair of.
• despair v. (Transitive) To cause to despair.
• despair v. (Intransitive, often with “of”) To be hopeless; to have no hope; to give up all hope or expectation.
DESPISE• despise v. To regard with contempt or scorn.
• despise v. To disregard or ignore.
• DESPISE v. to look down upon with contempt.
DESPITE• despite prep. In spite of, notwithstanding.
• despite n. (Obsolete) Disdain, contemptuous feelings, hatred.
• despite n. (Archaic) Action or behaviour displaying such feelings; an outrage, insult.
DESPOIL• despoil v. (Transitive) To plunder; to pillage; take spoil from.
• despoil v. (Transitive) To violently strip (someone), with indirect object of their possessions etc.; to rob.
• despoil v. (Obsolete, transitive or reflexive) To strip (someone) of their clothes; to undress.
DESPOND• despond v. To give up the will, courage, or spirit; to become dejected, lose heart.
• despond n. (Archaic) Despondency.
• DESPOND v. to lose heart.
DESPOTS• despots n. Plural of despot.
• DESPOT n. a ruler with absolute power and authority.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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