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There are 7 ten-letter words containing DESPO

DESPOILERS	• despoilers n. Plural of despoiler. • DESPOILER n. one who despoils.
DESPOILING	• despoiling v. Present participle of despoil. • DESPOILING n. the act of pillaging.
DESPONDENT	• despondent adj. In low spirits from loss of hope or courage. • DESPONDENT adj. feeling or showing extreme discouragement.
DESPONDING	• desponding v. Present participle of despond. • desponding adj. That causes despondency; disheartening. • desponding n. A feeling or expression of despondency.
DESPOTATES	• despotates n. Plural of despotate. • DESPOTATE n. a territory governed by a despot, also DESPOTAT.
DESPOTICAL	• despotical adj. Despotic. • DESPOTICAL adj. having the character of, or pertaining to, a despot, also DESPOTIC.
DESPOTISMS	• despotisms n. Plural of despotism. • DESPOTISM n. absolute power; a state governed by a despot.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 20 words
Scrabble in French: 2 words
Scrabble in Spanish: 87 words
Scrabble in Italian: 17 words
Scrabble in German: no word
Scrabble in Romanian: 38 words

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