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There are 13 eight-letter words containing ESOM

BESOMING• besoming v. Present participle of besom.
• BESOM v. to sweep with a besom.
BORESOME• boresome adj. Marked by boredom; boring; uninteresting.
• BORESOME adj. tedious, boring.
DOLESOME• dolesome adj. Doleful; dismal; gloomy.
• DOLESOME adj. doleful, dismal.
GAMESOME• gamesome adj. Full of sport; playful.
• GAMESOME adj. playful, merry, sportive.
GLEESOME• gleesome adj. Characterised or marked by glee; gleeful; joyous.
• GLEESOME adj. merry, also GLEEFUL.
GRUESOME• gruesome adj. Repellently frightful and shocking; horrific or ghastly.
• GRUESOME adj. repugnant, also GREWSOME.
HOLESOME• holesome adj. Obsolete form of wholesome.
• HOLESOME adj. (Spenser) wholesome, also HEALSOME, HOLESOM.
JOKESOME• jokesome adj. Marked by joking or jocularity; joky; humorous.
• JOKESOME adj. amusing.
LIFESOME• lifesome adj. (Poetic, obsolete) animated; gay; lively; sprightly.
• LIFESOME adj. full of life.
LONESOME• lonesome adj. Unhappy due to being alone; lonely.
• lonesome n. (Informal) Oneself alone.
• LONESOME adj. lonely.
LOVESOME• lovesome adj. Worthy of love; having qualities that inspire love; lovable.
• lovesome adj. (Now rare, chiefly Ireland) Affectionate; friendly.
• lovesome adj. Lovable on account of beauty; lovely, beautiful.
MESOMERE• mesomere n. A blastomere that is intermediate in size between a micromere and a macromere.
• MESOMERE n. an embryonic segment.
TIRESOME• tiresome adj. Causing fatigue or boredom; wearisome.
• TIRESOME adj. tedious.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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