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There are 4 twelve-letter words containing FENE

DEFENESTRATE	• defenestrate v. (Transitive) To eject or throw (someone or something) from or through a window. • defenestrate v. (Transitive) To throw out; to remove or dismiss (someone) from a position of power or authority. • defenestrate v. (Computing, transitive, humorous, slang) To remove a Windows operating system from a computer.
FENESTRATING	• fenestrating v. Present participle of fenestrate. • FENESTRATE v. to equip with windows.
FENESTRATION	• fenestration n. (Architecture) The arrangement of windows and similar openings in a building. • fenestration n. (Surgery, anatomy) An opening in the surface of an organ etc; the surgical creation of such an opening… • fenestration n. (Surgery, anatomy) An opening that occurs naturally or is created surgically, as through a biological membrane.
UNSAFENESSES	• UNSAFENESS n. the state of being unsafe.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 19 words
Scrabble in French: 23 words
Scrabble in Spanish: 13 words
Scrabble in Italian: 15 words
Scrabble in German: no word
Scrabble in Romanian: 1 word

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