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There are 4 six-letter words containing FILE

DEFILE• defile v. (Transitive).
• defile v. (Intransitive, obsolete).
• defile v. (Intransitive, archaic) To march in a single file or line; to file.
FILERS• filers n. Plural of filer.
• FILER n. a person or thing that files.
FILETS• filets n. Plural of filet.
• FILET v. to cut boneless slices from, also FILLET.
REFILE• refile v. (Transitive) To file again or differently.
• REFILE v. to file again.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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