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There are 20 eight-letter words containing FILE

BACKFILE• backfile n. A file of documents in paper or fiche format that have no digital equivalent.
• backfile n. A file containing non-current items.
• BACKFILE n. the back numbers of a newspaper.
DEFILERS• defilers n. Plural of defiler.
• DEFILER n. one who defiles.
FILEABLE• fileable adj. Capable of being filed (in various senses).
• FILEABLE adj. able to be filed.
FILECARD• filecard n. Alternative form of file card.
• file-card n. (Uncountable) Material with embedded wire teeth used for cleaning files; card-clothing.
• file-card n. (Countable) A tool for removing debris from between the teeth of a file.
FILEFISH• filefish n. Any fish of the family Monacanthidae, with very slender bodies.
• FILEFISH n. a kind of fish with roughly granulated skin, which is sometimes used in place of sandpaper.
FILEMOTS• FILEMOT n. (French) a dull brown colour, also PHILAMOT, PHILOMOT.
FILENAME• filename n. (Computing) The name assigned to a file in a file system.
• file␣name n. Alternative spelling of filename.
• FILENAME n. the name of a computer file.
FILETING• fileting v. Present participle of filet.
• FILET v. to cut boneless slices from, also FILLET.
METAFILE• metafile n. (Computing) A file in any format that can store multiple types of data, typically a graphics file format.
• METAFILE n. graphical information capable of being transferred between systems or software.
MISFILED• misfiled v. Simple past tense and past participle of misfile.
• MISFILE v. to file in the wrong place.
MISFILES• misfiles v. Third-person singular simple present indicative form of misfile.
• MISFILE v. to file in the wrong place.
NAILFILE• nailfile n. Alternative form of nail file.
• nail-file n. Alternative form of nail file.
• nail␣file n. A small file made of soft metal, or a board covered with fine sandpaper, for filing and shaping one’s…
PREFILED• prefiled v. Simple past tense and past participle of prefile.
• PREFILE v. to file beforehand.
PREFILES• prefiles v. Third-person singular simple present indicative form of prefile.
• PREFILE v. to file beforehand.
PROFILED• profiled v. Simple past tense and past participle of profile.
• PROFILE v. to draw an outline of.
PROFILER• profiler n. A mechanical device that cuts complex, irregular shapes by tracing a pattern.
• profiler n. A person who creates a profile for something or someone, especially a psychological profile for an unknown criminal.
• profiler n. (Computing) A software program that measures the performance of different portions of another program…
PROFILES• profiles n. Plural of profile.
• profiles v. Third-person singular simple present indicative form of profile.
• PROFILE v. to draw an outline of.
SERAFILE• serafile n. Alternative form of serrefile.
• SERAFILE n. men riding in the rear of a squadron.
SUBFILES• subfiles n. Plural of subfile.
• SUBFILE n. a subdivision of a file.
SWAPFILE• swapfile n. Alternative spelling of swap file.
• swap␣file n. (Computing) A file on disk used as auxiliary memory.
• SWAPFILE n. a computer file with space for transferred programs.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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