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There are 5 five-letter words containing IUM

ILIUM• ilium n. (Anatomy) The upper and widest of the three bones that make up each side of the hipbone and pelvis.
• ilium n. (Anatomy, obsolete) The ileum, part of the small intestine (In modern usage, misspelling of ileum.).
• Ilium prop.n. Troy.
ODIUM• odium n. Hatred; dislike.
• odium n. The quality that provokes hatred; offensiveness.
• ODIUM n. (Latin) hatred accompanied by contempt.
ONIUM• onium n. (Chemistry) any cation derived by the addition of a proton to the hydride of any element of the nitrogen…
• onium n. (Chemistry) any organic derivative of these compounds.
• onium n. (Physics) the bound pair of a particle and its antiparticle.
OPIUM• opium n. (Uncountable) A yellow-brown, addictive narcotic drug obtained from the dried juice of unripe pods of…
• opium n. (By extension, countable) Anything that numbs or stupefies.
• OPIUM n. an addictive narcotic.
PIUMS• PIUM n. (Tupi) a Brazilian biting fly.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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