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There are 3 eight-letter words containing IOE

BIOETHIC• bioethic n. A principle or system of bioethics.
• BIOETHIC adj. relating to ethical questions in biology.
DIOECIES• DIOECY n. the state of having separate male and female types.
DIOECISM• dioecism n. The devolution of a city into its formerly subordinate constituents, the opposite of synoecism.
• dioecism n. (Biology) The condition of being dioecious.
• DIOECISM n. the condition of being dioecious, having male and female sexual organs in different individuals.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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