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There are 9 twelve-letter words containing ISEC

DISECONOMIES• diseconomies n. Plural of diseconomy.
• DISECONOMY n. lack of economy; a factor responsible for an increase in cost.
MILLISECONDS• milliseconds n. Plural of millisecond.
• MILLISECOND n. a thousandth part of a second.
QUADRISECTED• quadrisected v. Simple past tense and past participle of quadrisect.
• QUADRISECT v. to divide into four equal parts.
TRISECTRICES• TRISECTRIX n. a certain curve of a polar equation.
VENISECTIONS• VENISECTION n. surgical incision into a vein.
VIVISECTIONS• vivisections n. Plural of vivisection.
• VIVISECTION n. the cutting of or operation on a living animal usually for physiological or pathological investigation.
VIVISECTORIA• vivisectoria n. Plural of vivisectorium.
• VIVISECTORIUM n. a place for vivisection.
WISECRACKERS• wisecrackers n. Plural of wisecracker.
• WISECRACKER n. one who wisecracks.
WISECRACKING• wisecracking adj. Making many wisecracks.
• wisecracking v. Present participle of wisecrack.
• wise-cracking adj. Alternative form of wisecracking.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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