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There are 4 seven-letter words containing ISTU

DISTUNE• distune v. (Transitive) To put (something) out of tune.
• distune v. (Transitive, figurative) To cause (something) not to be in harmony or to be poorly adjusted.
• DISTUNE v. to put out of tune.
DISTURB• disturb v. (Transitive) to confuse a quiet, constant state or a calm, continuous flow, in particular: thoughts…
• disturb v. (Transitive) to divert, redirect, or alter by disturbing.
• disturb v. (Intransitive) to have a negative emotional impact; to cause emotional distress or confusion.
FISTULA• fistula n. (Medicine) An abnormal connection or passageway between organs or vessels that normally do not connect.
• fistula n. (Rare) A tube, a pipe, or a hole.
• fistula n. (Christianity, historical) The tube through which the wine of the Eucharist was once sucked from the…
MISTUNE• mistune v. (Transitive) To tune wrongly.
• mistune n. An incorrect tuning.
• MISTUNE v. to tune incorrectly.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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