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There are 9 twelve-letter words containing LONE

ANTICYCLONES• anticyclones n. Plural of anticyclone.
• ANTICYCLONE n. a system of winds that rotates clockwise in the northern hemisphere and counterclockwise in the southern.
COLONELLINGS• COLONELLING n. (archaic) playing the colonel.
COLONELSHIPS• colonelships n. Plural of colonelship.
• COLONELSHIP n. the office of colonel.
LONELINESSES• lonelinesses n. Plural of loneliness.
• LONELINESS n. the state of being lonely.
LONESOMENESS• lonesomeness n. The state of being lonesome.
• LONESOMENESS n. the state of being lonesome.
MESOCYCLONES• mesocyclones n. Plural of mesocyclone.
• MESOCYCLONE n. a rapidly rotating air mass within a thunderstorm that often gives rise to a tornado.
METHAQUALONE• methaqualone n. (Pharmacology) A sedative drug that has effects similar to barbiturates. Also used recreationally.
• METHAQUALONE n. a type of sedative, aka quaalude.
PREDNISOLONE• prednisolone n. (Pharmacology) A synthetic glucocorticoid C21H28O5 that is a dehydrogenated analog of cortisol and is…
• PREDNISOLONE n. a drug similar to cortisone, used as an anti-inflammatory, also PREDNISONE.
PREGNENOLONE• pregnenolone n. (Biochemistry, steroids) A steroid prohormone involved in the steroidogenesis of progesterone, mineralocorticoids…
• PREGNENOLONE n. a steroid ketone formed by the oxidation of steroids and yielding progesterone on dehydrogenation.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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