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There are 4 twelve-letter words containing OSEM

CLOSEMOUTHED• closemouthed adj. Reticent, secretive or uncommunicative.
• CLOSEMOUTHED adj. cautious in speaking.
GALACTOSEMIA• galactosemia n. (Medicine) A genetic metabolic disorder characterized by an inability to metabolize galactose properly.
• galactosemia n. The presence of galactose in the blood.
• GALACTOSEMIA n. the presence of galactose in the blood, also GALACTOSAEMIA.
GALACTOSEMIC• galactosemic n. One who has galactosemia.
• galactosemic adj. Having or relating to galactosemia.
• GALACTOSEMIC adj. relating to galactosemia, the presence of galactose in the blood, also GALACTOSAEMIC.
TSCHERNOSEMS• tschernosems n. Plural of tschernosem.
• TSCHERNOSEM n. (Russian) a very fertile soil of subhumid steppe, also CHERNOZEM.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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