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There are 20 eight-letter words containing OPEN

AUTOPENS• autopens n. Plural of autopen.
• AUTOPEN n. a mechanical device used to produce imitation signatures.
LYCOPENE• lycopene n. (Organic chemistry) A red carotenoid pigment found in tomatoes, other red vegetables, and in animal…
• LYCOPENE n. a red pigment.
OPENABLE• openable adj. Capable of being opened.
• OPENABLE adj. able to be opened.
OPENCAST• opencast adj. (Chiefly Britain) Of or pertaining to strip mining, in which material is removed from a surface that has been exposed.
• open-cast adj. Alternative form of opencast.
• OPENCAST adj. excavated from an open air site.
OPENINGS• openings n. Plural of opening.
• OPENING n. a vacant space.
OPENNESS• openness n. Accommodating attitude or opinion, as in receptivity to new ideas, behaviors, cultures, peoples, environments…
• openness n. The degree to which a person, group, organization, institution, or society exhibits this liberal attitude or opinion.
• openness n. Lack of secrecy; candour, transparency.
OPENSIDE• openside n. (Rugby) The space on the side of the pitch with the larger distance between the breakdown/set piece and the touchline.
• openside n. (Rugby union) Short for openside flanker.
• open-side n. (Rugby) the portion of the field which is larger as measured from a scrum or breakdown to the touchline.
OPENWORK• openwork n. Any of several forms of metalwork or needlework having decorative openings.
• openwork n. (Mining) A quarry; an open cut.
• open-work n. Alternative spelling of openwork.
PROPENAL• propenal n. (Organic chemistry) The compound acrolein.
• PROPENAL n. another name for acrolein.
PROPENDS• propends v. Third-person singular simple present indicative form of propend.
• PROPEND v. (Shakespeare) to have a tendency toward.
PROPENES• propenes n. Plural of propene.
• PROPENE n. a flammable gas.
PROPENOL• PROPENOL n. a flammable gas.
PROPENSE• propense adj. (Archaic) Leaning toward, in a moral sense; inclined; disposed; prone.
• PROPENSE adj. (obsolete) inclined.
PROPENYL• propenyl n. (Chemistry) A radical of propene (propylene).
• PROPENYL n. a hydrocarbon radical related to propene.
REOPENED• reopened v. Past participle of reopen.
• REOPEN v. to open again.
REOPENER• reopener n. Anything that reopens.
• REOPENER n. a clause in a contract for reconsideration.
SEMIOPEN• semiopen adj. Partly open.
• SEMIOPEN adj. partly open.
TWOPENCE• twopence n. (Britain, Ireland) A British or Irish coin worth two (old or new) pence.
• twopence n. (Britain, Ireland) A cost or value of two pence.
• twopence n. (Britain, Ireland) (by extension) A small amount or value.
TWOPENNY• twopenny adj. Having a value or cost of twopence.
• twopenny adj. Cheap; worthless; petty.
• twopenny n. (Britain, countable, dated) A coin or stamp worth two pence.
UNOPENED• unopened adj. Not yet opened; still closed.
• UNOPENED adj. not opened.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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