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There are 14 twelve-letter words containing OPERAT

COOPERATIONS• cooperations n. Plural of cooperation.
• coöperations n. Plural of coöperation.
• COOPERATION n. the action of cooperating.
COOPERATIVES• cooperatives n. Plural of cooperative.
• co-operatives n. Plural of co-operative.
• COOPERATIVE n. an enterprise or organization owned by and operated for the benefit of those using its services.
DISOPERATION• DISOPERATION n. a mutually harmful relationship between two organisms in a community.
INTEROPERATE• interoperate v. (Intransitive, computing) To work reliably with another system.
NONOPERATING• nonoperating adj. Not operating.
• nonoperating adj. Not of or pertaining to operation.
• non-operating adj. Alternative form of nonoperating.
NONOPERATIVE• nonoperative adj. Not requiring or involving a medical operation or surgery.
• nonoperative adj. Not operative, not operational; inoperative.
• nonoperative n. (Uncommon) One who is not an operative (“employee or worker”).
OPERATICALLY• operatically adv. In an operatic manner.
• OPERATIC adv. relating to opera.
OPERATIONISM• operationism n. (Philosophy) The doctrine that the meaning of a term consists of the operation(s) performed in defining it.
• OPERATIONISM n. the theory that defines scientific concepts by means of the operations used to prove or determine them, also OPERATIONALISM.
OPERATIONIST• operationist n. A proponent of operationism.
• OPERATIONIST n. an adherent of operationism.
OPERATORLESS• operatorless adj. Without an operator (person who operates); fully automatic.
• OPERATORLESS adj. without an operator.
OVEROPERATED• overoperated v. Simple past tense and past participle of overoperate.
• OVEROPERATE v. to operate to excess.
OVEROPERATES• overoperates v. Third-person singular simple present indicative form of overoperate.
• OVEROPERATE v. to operate to excess.
PREOPERATIVE• preoperative adj. Prior to surgery.
• preoperative n. A transgender person who has not yet undergone gender reassignment surgery.
• PREOPERATIVE adj. occurring before a surgical operation.
REOPERATIONS• reoperations n. Plural of reoperation.
• REOPERATION n. operation again.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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