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There are 5 four-letter words containing RUG

DRUG• drug n. (Pharmacology) A substance used to treat an illness, relieve a symptom, or modify a chemical process…
• drug n. A psychoactive substance, especially one which is illegal and addictive, ingested for recreational use…
• drug n. Anything, such as a substance, emotion, or action, to which one is addicted.
FRUG• frug n. (Usually preceded by definite article) A dance derived from the twist, popular in the 1960s.
• frug v. (Intransitive) To perform this dance.
• FRUG v. to perform a type of vigorous dance.
RUGA• ruga n. (Anatomy, zootomy, botany, usually in the plural) A fold, crease or wrinkle.
• RUGA n. (Latin) an anatomical fold or wrinkle.
RUGS• rugs n. Plural of rug.
• Rugs n. Plural of Rug.
• RUG v. (Scots) to pull roughly.
TRUG• trug n. (Chiefly Britain) A shallow, oval basket used for gardening.
• trug n. (Obsolete) A trough or tray.
• trug n. (Obsolete) A hod for mortar.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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