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There are 11 six-letter words containing RAIN

BRAINS• brains n. Plural of brain.
• brains n. The substance of a brain, as a material or foodstuff.
• brains n. (Informal) The figurative substance of a brain: mental ability, intelligence.
BRAINY• brainy adj. (Informal) Very intellectually capable.
• BRAINY adj. intelligent.
DRAINS• drains n. Plural of drain.
• drains v. Third-person singular simple present indicative form of drain.
• Drains prop.n. Plural of Drain.
GRAINE• GRAINE n. silkworm eggs.
GRAINS• grains n. Pigeons’ dung used in tanning. See grainer.
• grains n. Plural of grain.
• grains v. Third-person singular simple present indicative form of grain.
GRAINY• grainy adj. Resembling grains; granular.
• grainy adj. Coarsely ground or gritty.
• GRAINY adj. having a grain.
RAINED• rained v. Simple past tense and past participle of rain.
• RAIN v. to fall in drops of water.
RAINES• raines n. Plural of raine.
• Raines n. (Historical) A type of fine linen once imported from France.
• Raines prop.n. A surname.
SPRAIN• sprain v. To weaken, as a joint, ligament, or muscle, by sudden and excessive exertion, as by wrenching; to overstrain…
• sprain n. The act or result of spraining; lameness caused by spraining.
• SPRAIN v. to injure by twisting or wrenching.
STRAIN• strain n. (Archaic) Race; lineage, pedigree.
• strain n. (Biology) A particular variety of a microbe, virus, or other organism, usually a taxonomically infraspecific one.
• strain n. (Figurative) Hereditary character, quality, tendency, or disposition.
TRAINS• trains n. Plural of train.
• trains v. Third-person singular simple present indicative form of train.
• Trains prop.n. Plural of Train.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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