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There are 11 six-letter words containing RAIN

BRAINSbrains n. Plural of brain.
brains n. The substance of a brain, as a material or foodstuff.
brains n. (Informal) The figurative substance of a brain: mental ability, intelligence.
BRAINYbrainy adj. (Informal) Very intellectually capable.
BRAINY adj. intelligent.
DRAINSdrains n. Plural of drain.
drains v. Third-person singular simple present indicative form of drain.
Drains prop.n. Plural of Drain.
GRAINEGRAINE n. silkworm eggs.
GRAINSgrains n. Pigeons’ dung used in tanning. See grainer.
grains n. Plural of grain.
grains v. Third-person singular simple present indicative form of grain.
GRAINYgrainy adj. Resembling grains; granular.
grainy adj. Coarsely ground or gritty.
GRAINY adj. having a grain.
RAINEDrained v. Simple past tense and past participle of rain.
RAIN v. to fall in drops of water.
RAINESraines n. Plural of raine.
Raines n. (Historical) A type of fine linen once imported from France.
Raines prop.n. A surname.
SPRAINsprain v. To weaken, as a joint, ligament, or muscle, by sudden and excessive exertion, as by wrenching; to overstrain…
sprain n. The act or result of spraining; lameness caused by spraining.
SPRAIN v. to injure by twisting or wrenching.
STRAINstrain n. (Archaic) Race; lineage, pedigree.
strain n. (Biology) A particular variety of a microbe, virus, or other organism, usually a taxonomically infraspecific one.
strain n. (Figurative) Hereditary character, quality, tendency, or disposition.
TRAINStrains n. Plural of train.
trains v. Third-person singular simple present indicative form of train.
Trains prop.n. Plural of Train.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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