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There are 18 six-letter words containing SPU

SPUDDY• spuddy adj. Short and fat.
• spuddy adj. (Slang) Resembling or characteristic of potatoes.
• SPUDDY adj. podgy.
SPUERS• SPUER n. one who spues, also SPEWER.
SPUGGY• spuggy n. (Geordie, Teesside, Scotland) sparrow.
• SPUGGY n. (Scots) a house sparrow, also SPUG, SPEUG.
SPUING• spuing v. Present participle of spue.
• SPUE v. (archaic) to spew.
SPULES• SPULE n. (Scots) the shoulder, also SPALD, SPALLE, SPAUL, SPAULD, SPEAL.
SPULYE• spulye n. Obsolete form of spulzie.
• spulye v. Obsolete form of spulzie.
• SPULYE v. (Scots) to plunder, also SPUILZIE, SPULYIE, SPULZIE.
SPUMED• spumed v. Simple past tense and past participle of spume.
• SPUME v. to foam.
SPUMES• spumes n. Plural of spume.
• spumes v. Third-person singular simple present indicative form of spume.
• SPUME v. to foam.
SPUNGE• spunge n. Obsolete form of sponge.
• spunge v. Obsolete form of sponge.
• SPUNGE n. (obsolete) a sponge.
SPUNKS• spunks v. Third-person singular simple present indicative form of spunk.
• SPUNK v. to begin to burn.
SPUNKY• spunky adj. Spirited or plucky.
• spunky adj. (UK) Pertaining to or like spunk (semen).
• spunky adj. (UK) Stained with semen.
SPURGE• spurge n. Any plant of the genus Euphorbia, a diverse genus of over 2,000 species.
• spurge v. (Intransitive) To emit foam; to froth; said of the emission of yeast from beer during fermentation.
• SPURGE n. a plant of genus Euphorbia, usually having a milky juice which yields powerful emetic and cathartic products.
SPURNE• SPURNE v. (Spenser) to spur.
SPURNS• spurns v. Third-person singular simple present indicative form of spurn.
• spurns n. Plural of spurn.
• SPURN v. to reject with contempt.
SPURRY• spurry n. Any of several European annual herbs of the genus Spergula.
• SPURRY adj. spur-like.
• SPURRY n. an annual herb with whorled filiform leaves, sometimes grown for fodder, also SPURREY.
SPURTS• spurts n. Plural of spurt.
• spurts v. Third-person singular simple present indicative form of spurt.
• SPURT v. to gush forth, also SPIRT.
SPUTUM• sputum n. (Physiology) Matter coughed up and expectorated from the mouth, composed of saliva and discharges from…
• SPUTUM n. (Latin) thick mucus coughed up from the respiratory tract esp in certain diseases of the lungs, chest, or throat.
UNSPUN• unspun adj. Not spun.
• unspun adj. Of fibers, not yet having been twisted into yarn or thread.
• UNSPUN adj. not spun.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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