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There are 17 twelve-letter words containing SPLE

DISPLEASANCE• displeasance n. (Obsolete) Displeasure, dissatisfaction.
• DISPLEASANCE n. (Spenser) displeasure.
DISPLEASANTS• DISPLEASANT v. to render unpleasing.
DISPLEASEDLY• displeasedly adv. In a displeased manner.
• DISPLEASED adv. DISPLEASE, to offend, to annoy.
DISPLEASURED• displeasured v. Simple past tense and past participle of displeasure.
• DISPLEASURE v. (archaic) to displease.
DISPLEASURES• displeasures n. Plural of displeasure.
• DISPLEASURE v. (archaic) to displease.
DISPLENISHED• displenished v. Simple past tense and past participle of displenish.
• DISPLENISH v. to deprive or strip, as a house of furniture, or a barn of stock.
DISPLENISHES• displenishes v. Third-person singular simple present indicative form of displenish.
• DISPLENISH v. to deprive or strip, as a house of furniture, or a barn of stock.
MISPLEADINGS• mispleadings n. Plural of mispleading.
• MISPLEADING n. an error in pleading.
RESPLENDENCE• resplendence n. The property of being, or that which causes something to be, resplendent.
• RESPLENDENCE n. the state of being resplendent, also RESPLENDENCY.
RESPLENDENCY• resplendency n. Resplendence, radiant beauty.
• resplendency n. (Mathematics) A property of the truth of sentence structures in Peano arithmetic.
• RESPLENDENCY n. the state of being resplendent, also RESPLENDENCE.
SPLEENSTONES• spleen␣stones n. Plural of spleen stone.
• SPLEENSTONE n. (obsolete) jade.
SPLENDIDIOUS• splendidious adj. (Obsolete) splendid.
• SPLENDIDIOUS adj. (obsolete) splendid, also SPLENDIDOUS.
SPLENDIDNESS• splendidness n. The state or the quality of being splendid.
• splendidness n. Something that is splendid.
• SPLENDIDNESS n. the state of being splendid.
SPLENISATION• splenisation n. Britain standard spelling of splenization.
• SPLENISATION n. conversion (e.g. of the lung) into a spongy, spleen-like substance, also SPLENIZATION.
SPLENIZATION• splenization n. (Medicine) A morbid state of the lung produced by inflammation, in which its tissue resembles that of the spleen.
• SPLENIZATION n. conversion (e.g. of the lung) into a spongy, spleen-like substance, also SPLENISATION.
SPLENOMEGALY• splenomegaly n. (Pathology) An enlargement of the spleen.
• SPLENOMEGALY n. abnormal enlargement of the spleen.
SPORTSPLEXES• sportsplexes n. Plural of sportsplex.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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