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There are 5 eight-letter words containing SICO

BURSICON	• bursicon n. (Biochemistry) A heterodimeric protein that is an insect hormone which mediates tanning in the cuticle of adult flies. • BURSICON n. a hormone produced by the insect brain that regulates processes associated with ecdysis.
CLASSICO	• CLASSICO adj. made from grapes grown in a certain part of Italy.
MASSICOT	• massicot n. (Chemistry) lead monoxide, PbO, obtained as a yellow amorphous powder, the fused and crystalline form… • MASSICOT n. (French) yellow lead monoxide, also MASTICOT.
PERSICOS	• PERSICO n. (French) a cordial made of the kernels of apricots, nectarines, etc. with refined spirit, also PERSICOT.
PERSICOT	• persicot n. A cordial made of the kernels of apricots, nectarines, etc., with refined spirit. • PERSICOT n. (French) a cordial made of the kernels of apricots, nectarines, etc. with refined spirit, also PERSICO.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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English Wiktionary: 11 words
Scrabble in French: 4 words
Scrabble in Spanish: 26 words
Scrabble in Italian: 25 words
Scrabble in German: no word
Scrabble in Romanian: 7 words

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