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There are 3 eight-letter words containing TRILE

LAETRILE• laetrile n. A drug, derived from the amygdalin of apricot kernels, once thought capable of destroying cancer cells…
• LAETRILE n. (tradename) a drug derived from apricot pits, used in the treatment of cancer.
NITRILES• nitriles n. Plural of nitrile.
• NITRILE n. any organic cyanide compound in which an alkyl group is directly attached to the carbon of a cyanide group, also NITRIL.
TRILEMMA• trilemma n. A circumstance in which a choice must be made between three options that seem equally undesirable.
• trilemma n. A situation in which a choice must be made among three desirable options, only two of which are possible…
• trilemma n. (Logic) An argument containing three alternatives, jointly exhaustive either under any condition(s)…

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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