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There are 16 ten-letter words containing UPTI

ABRUPTIONS• abruptions n. Plural of abruption.
• ABRUPTION n. a sudden, violent separation.
CORRUPTING• corrupting v. Present participle of corrupt.
• CORRUPT v. to make bad, debase.
CORRUPTION• corruption n. The act of corrupting or of impairing integrity, virtue, or moral principle; the state of being corrupted…
• corruption n. The act of corrupting or making putrid, or state of being corrupt or putrid; decomposition or disorganization…
• corruption n. The product of corruption; putrid matter.
CORRUPTIVE• corruptive adj. Tending to corrupt.
• CORRUPTIVE adj. tending to corrupt.
DISRUPTING• disrupting v. Present participle of disrupt.
• disrupting adj. That disrupts; disruptive.
• DISRUPT v. to throw into confusion.
DISRUPTION• disruption n. An interruption to the regular flow or sequence of something.
• disruption n. A continuing act of disorder.
• disruption n. A breaking or bursting apart; a breach.
DISRUPTIVE• disruptive adj. Causing disruption or unrest.
• disruptive adj. (Business) Causing major change, as in a market.
• DISRUPTIVE adj. causing disruption.
ERUPTIONAL• eruptional adj. Eruptive.
• ERUPTIONAL adj. eruptive.
ERUPTIVELY• eruptively adv. In an eruptive manner.
• ERUPTIVE adv. breaking out or bursting forth.
ERUPTIVITY• eruptivity n. The state or quality of being eruptive.
• ERUPTIVITY n. the state of being eruptive.
GOLUPTIOUS• goluptious adj. Splendid, delightful, magnificent.
• GOLUPTIOUS adj. (slang) delicious, voluptuous, also GOLOPTIOUS.
IRRUPTIONS• irruptions n. Plural of irruption.
• IRRUPTION n. a forcible or violent rush; a breaking in.
NUPTIALITY• nuptiality n. The state of being married.
• NUPTIALITY n. nuptial character or quality.
PRENUPTIAL• prenuptial adj. Occurring before marriage; antenuptial.
• prenuptial n. (US) Synonym of prenuptial agreement.
• pre-nuptial adj. Alternative spelling of prenuptial.
UPTIGHTEST• uptightest adj. Superlative form of uptight: most uptight.
• UPTIGHT adj. tense; straitlaced.
UPTITLINGS• UPTITLING n. the practise of conferring grandiose titles on employees doing relatively menial jobs.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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